A Relentless Molecular Pursuit on Behalf of Patients with Refractory or Rare Cancer

Date(s) - 19 Mar 2013
12:00 PM - 1:30 PM

Kiewit Auditorium, Arizona Cancer Center

Daniel D. Von Hoff, MD, FACP, is currently Physician in Chief and Distinguished Professor of the Translational Genomics Research Institute (TGen) in Phoenix. He is also Chief Scientific Officer for Scottsdale Healthcare’s Clinical Research Institute and holds several other titles with national organizations and research programs. Dr. Von Hoff’s major interest is in the development of new anticancer agents. both in the clinic and in the laboratory. He and his colleagues were involved in the beginning of the development of many of the agents we now use routinely. Dr. Von Hoff is widely published and in 2010 received the David. A. Karnofsky Memorial Award from the American Society of Clinical Onocology for the outstanding contributions to cancer research leading to significant improvements in patient care.

Pancreatic cancer is the fourth-leading cause of death from cancer in the United States. It has the worst 1- and 5- year survival rates of any cancer. The only way to early detection, prevention or cure of the disease is through the application of the best science we can master. This lecture will demonstrate how the survival rate for patients with advanced pancreatic cancer has improved through the genomic profiling of pancreatic cancer tumor cells, the characterization of tumor stroma and the study of how pancreatic cancer cells use “fuel”.

An unexpected finding while melecularly profiling patients’ cancers is the finding that rare cancers (e.g. acinar cell, adenosquamous cell, salivary gland tumors, and others) often have a single mutation or abnormality which “drives” that cancer. Using a targeted agent for treating patients with rare cancers can produce dramatic shrinkage of their cancers.

This lecture will be video streamed -streaming.biocom.arizona.edu/home

Sponsored by Flinn Foundation

“A Relentless Molecular Pursuit on Behalf of Patients with Refractory or Rare Cancer” is a free event.

The Donald K. Buffmire Visiting Lectureship in Medicine, begun in 1997, continues the Flinn Foundation’s commitment to bringing to Arizona leading practitioners and thinkers in the medical field.

Questions, contact Rebecca Parada, 520-626-6177 or reparada@email.arizona.edu

Pay parking is available in the UMC garage or metered parking in the 2030 lot on Martin and Mabel